This first edition of the SDB implementation guide provides practical and easy-to-follow guidance in how to establish and implement SDB programming during an outbreak of Ebola virus disease or similar diseases. It provides tools and guidance to ensure that SDB programming both meets the need to prevent and control infection, and respects the dignity and humanity of the deceased and their communities. The manual is not only a go-to guide for personnel who must rapidly establish a quality SDB system at the first declaration of an outbreak requiring such services, it is also a useful resource for emergency preparedness in countries at risk from these deadly diseases. Finally, information on ensuring the safety of those carrying out SDBs is included, recognizing that the crucial work carried out by these life-saving teams is often dangerous.