Following the publication of 'A review of the science of Low Template DNA Analysis' by Professor Brian Caddy, the Forensic Science Regulator (FSR) commissioned Professor Peter Gill to provide advice on the level of consensus in the interpretation of DNA profiles and mixed profiles. The FSR adopted a set of principles in a descriptive rather than prescriptive manner that described the UK consensus regarding the features that an interpretation methodology should have to interpret DNA profiles, especially those that are complex in some way because the target material is at a low level (or degraded).